Tzvetkov, Mladen V.: шукати на сайті Z-Library

Kirchheiner, Julia, Henckel, Hanns-Benjamin, Franke, Leonora, Meineke, Ingolf, Tzvetkov, Mladen, Uebelhack, Ralf, Roots, Ivar, Brockmöller, Jürgen

Рік:

2015

Мова:

english

Файл:

PDF, 1.35 MB

english, 2015

Impact of the CYP2D6 ultra-rapid metabolizer genotype on doxepin pharmacokinetics and serotonin in platelets

Журнал:

Рік:

2005

Мова:

english

Файл:

PDF, 142 KB

english, 2005

Heritability of caffeine metabolism: Environmental effects masking genetic effects on CYP1A2 activity but not on NAT2

Matthaei, Johannes, Tzvetkov, Mladen V, Strube, Jakob, Sehrt, Daniel, Sachse-Seeboth, Cordula, Hjelmborg, Jakob B, Möller, Sören, Halekoh, Ulrich, Hofmann, Ute, Schwab, Matthias, Kerb, Reinhold, Brock

Журнал:

Tzvetkov, Mladen V., Matthaei, Johannes, Pojar, Sherin, Faltraco, Frank, Vogler, Sabrina, Prukop, Thomas, Seitz, Tina, Brockmöller, Jürgen

Рік:

2016

Мова:

english

Файл:

PDF, 1.04 MB

english, 2016

Increased systemic exposure and stronger cardiovascular and metabolic adverse reactions to fenoterol in individuals with heritable OCT1 deficiency

Журнал:

Jensen, Ole, Matthaei, Johannes, Blome, Felix, Schwab, Matthias, Tzvetkov, Mladen V., Brockmöller, Jürgen

Рік:

2017

Мова:

english

Файл:

PDF, 6.34 MB

english, 2017

Variability and heritability of thiamine pharmacokinetics with focus on OCT1 effects on membrane transport and pharmacokinetics in humans

Журнал:

Journal of Controlled Release

Рік:

2019

Мова:

english

Файл:

PDF, 2.04 MB

english, 2019

In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI

Sager, Maximilian, Grimm, Michael, Aude, Philipp, Schick, Philipp, Merdivan, Simon, Hasan, Mahmoud, Kromrey, Marie-Luise, Sivert, Aurélien, Benameur, Hassan, Koziolek, Mirko, Tzvetkov, Mladen V., Weit

Журнал:

Рік:

2019

Мова:

english

Файл:

PDF, 2.79 MB

english, 2019

Genome-wide single-nucleotide polymorphism arrays demonstrate high fidelity of multiple displacement-based whole-genome amplification

Mladen V. Tzvetkov, Christian Becker, Bettina Kulle, Peter Nürnberg, Jürgen Brockmöller, Leszek Wojnowski

Журнал:

ELECTROPHORESIS

Рік:

2005

Мова:

english

Файл:

PDF, 200 KB

english, 2005

Application of genomewide SNP arrays for detection of simulated susceptibility loci

Bettina Kulle, Markus Schirmer, Mohammad R. Toliat, Anita Suk, Christian Becker, Mladen Vassilev Tzvetkov, Jürgen Brockmöller, Heike Bickeböller, Gerd Hasenfuss, Peter Nürnberg, Leszek Wojnowski

Журнал:

Human Mutation

Рік:

2005

Мова:

english

Файл:

PDF, 250 KB

english, 2005

Topoisomerase II beta expression level correlates with doxorubicin-induced apoptosis in peripheral blood cells

Gisela Kersting, Mladen V. Tzvetkov, Klaus Huse, Bettina Kulle, Verena Hafner, Jürgen Brockmöller, Leszek Wojnowski

Журнал:

Naunyn-Schmiedeberg's Archives of Pharmacology

Рік:

2006

Мова:

english

Файл:

PDF, 342 KB

english, 2006

Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers

Stefan Viktor Vormfelde, Daniel Sehrt, Daniela Bolte, Susanne Pahl, Mladen Tzvetkov, Jürgen Brockmöller

Журнал:

European Journal of Clinical Pharmacology

Рік:

2006

Мова:

english

Файл:

PDF, 242 KB

english, 2006

Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

Jürgen Brockmöller, Mladen V. Tzvetkov

Журнал:

European Journal of Clinical Pharmacology

Рік:

2008

Мова:

english

Файл:

PDF, 691 KB

english, 2008

Relation Between Renal Dysfunction Requiring Renal Replacement Therapy and Promoter Polymorphism of the Erythropoietin Gene in Cardiac Surgery

Aron F. Popov, Egbert G. Schulz, Jan D. Schmitto, Kasim O. Coskun, Mladen V. Tzvetkov, Stephan Kazmaier, Janna Zimmermann, Friedrich A. Schöndube, Michael Quintel, José Hinz

Журнал:

Artificial Organs

Рік:

2010

Мова:

english

Файл:

PDF, 103 KB

english, 2010

No association of vitamin D metabolism-related polymorphisms and melanoma risk as well as melanoma prognosis: a case–control study

Annika Schäfer, Steffen Emmert, Jochen Kruppa, Steffen Schubert, Mladen Tzvetkov, Rotraut Mössner, Kristian Reich, Carola Berking, Matthias Volkenandt, Claudia Pföhler, Michael P. Schön, Thomas Vogt,

Журнал:

Archives of Dermatological Research

Рік:

2012

Мова:

english

Файл:

PDF, 239 KB

english, 2012

Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Annett Kühne, Mladen Vassilev Tzvetkov, Yohannes Hagos, Hermann Lage, Gerhard Burckhardt, Jürgen Brockmöller

Журнал:

Biochemical Pharmacology

Рік:

2009

Мова:

english

Файл:

PDF, 400 KB

english, 2009

The prototypic pharmacogenetic drug debrisoquine is a substrate of the genetically polymorphic organic cation transporter OCT1

Ali R. Saadatmand, Sina Tadjerpisheh, Jürgen Brockmöller, Mladen V. Tzvetkov

Журнал:

Biochemical Pharmacology

Рік:

2012

Мова:

english

Файл:

PDF, 437 KB

english, 2012

Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms

Stefan Viktor Vormfelde, Imke Hoell, Mladen Tzvetkov, Katja Jamrozinski, Daniel Sehrt, Jürgen Brockmöller, Eric Leibing

Журнал:

Journal of Psychiatric Research

Рік:

2006

Мова:

english

Файл:

PDF, 206 KB

english, 2006

Corrigendum to “Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms” [J Psychiatr Res 40 (2006) 568–576]

Stefan Viktor Vormfelde, Imke Hoell, Mladen Tzvetkov, Katja Jamrozinski, Daniel Sehrt, Jürgen Brockmöller, Eric Leibing

Журнал:

Journal of Psychiatric Research

Рік:

2008

Мова:

english

Файл:

PDF, 55 KB

english, 2008

Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine

Mladen Vassilev Tzvetkov, Cornelia Meineke, Elke Oetjen, Karen Hirsch-Ernst, Jürgen Brockmöller

Журнал:

Gene

Рік:

2007

Мова:

english

Файл:

PDF, 865 KB

english, 2007

Lithium enhances CRTC oligomer formation and the interaction between the CREB coactivators CRTC and CBP — Implications for CREB-dependent gene transcription

Annette Heinrich, Anne Sophie von der Heyde, Ulrike Böer, Do Thanh Phu, Mladen Tzvetkov, Elke Oetjen

Журнал:

Cellular Signalling

Рік:

2013

Мова:

english

Файл:

PDF, 1.62 MB

english, 2013

Phytate utilization by genetically engineered lysine-producing Corynebacterium glutamicum

Mladen V. Tzvetkov, Wolfgang Liebl

Журнал:

Journal of Biotechnology

Рік:

2008

Мова:

english

Файл:

PDF, 346 KB

english, 2008

Pharmacogenetic analyses of cisplatin-induced nephrotoxicity indicate a renoprotective effect of ERCC1 polymorphisms

Tzvetkov, Mladen V, Behrens, Gerrit, O’Brien, Valerie P, Hohloch, Karin, Brockmöller, Jürgen, Benöhr, Peter

Журнал:

Tzvetkov, Mladen V., dos Santos Pereira, Joao N., Meineke, Ingolf, Saadatmand, Ali R., Stingl, Julia C., Brockmöller, Jürgen

Рік:

2011

Мова:

english

Файл:

PDF, 873 KB

english, 2011

Molecular genetic analysis of 16 XP-C patients from Germany: environmental factors predominately contribute to phenotype variations

Schäfer, Annika, Hofmann, Lars, Gratchev, Alexei, Laspe, Petra, Schubert, Steffen, Schürer, Anke, Ohlenbusch, Andreas, Tzvetkov, Mladen, Hallermann, Christian, Reichrath, Jörg, Schön, Michael P., Emme

Журнал:

Experimental Dermatology

Рік:

2013

Мова:

english

Файл:

PDF, 359 KB

english, 2013

Morphine is a substrate of the organic cation transporter OCT1 and polymorphisms in OCT1 gene affect morphine pharmacokinetics after codeine administration

Журнал:

Biochemical Pharmacology

Рік:

2013

Мова:

english

Файл:

PDF, 1.68 MB

english, 2013

Genetic Polymorphisms in 11β-Hydroxysteroid Dehydrogenase Type 1 Correlate With the Postdexamethasone Cortisol Levels and Bone Mineral Density in Patients Evaluated for Osteoporosis

Siggelkow, Heide, Etmanski, Michael, Bozkurt, Sarayi, Groβ, Parissa, Koepp, Regine, Brockmöller, Jürgen, Tzvetkov, Mladen V.

Журнал:

Journal of Clinical Endocrinology & Metabolism

Рік:

2014

Мова:

english

Файл:

PDF, 934 KB

english, 2014

Carvedilol pharmacokinetics and pharmacodynamics in relation to CYP2D6 and ADRB pharmacogenetics

Sehrt, Daniel, Meineke, Ingolf, Tzvetkov, Mladen, Gültepe, Senol, Brockmöller, Jürgen

Журнал:

Dos Santos Pereira, Joao N., Tadjerpisheh, Sina, Abed, Manar Abu, Saadatmand, Ali R., Weksler, Babette, Romero, Ignacio A., Couraud, Pierre-Olivier, Brockmöller, Jürgen, Tzvetkov, Mladen V.

Рік:

2011

Мова:

english

Файл:

PDF, 871 KB

english, 2011

The Poorly Membrane Permeable Antipsychotic Drugs Amisulpride and Sulpiride Are Substrates of the Organic Cation Transporters from the SLC22 Family

Журнал:

The AAPS Journal

Рік:

2014

Мова:

english

Файл:

PDF, 575 KB

english, 2014

Functional and molecular genetic analyses of nine newly identified XPD -deficient patients reveal a novel mutation resulting in TTD as well as in XP/CS complex phenotypes

Schäfer, Annika, Gratchev, Alexei, Seebode, Christina, Hofmann, Lars, Schubert, Steffen, Laspe, Petra, Apel, Antje, Ohlenbusch, Andreas, Tzvetkov, Mladen, Weishaupt, Carsten, Oji, Vinzenz, Schön, Mich

Журнал:

Experimental Dermatology

Рік:

2013

Мова:

english

Файл:

PDF, 284 KB

english, 2013

PharmGKB summary

Gong, Li, Stamer, Ulrike M., Tzvetkov, Mladen V., Altman, Russ B., Klein, Teri E.

Журнал:

Heinrich, Annette, Böer, Ulrike, Tzvetkov, Mladen, Oetjen, Elke, Knepel, Willhart

Рік:

2014

Мова:

english

Файл:

PDF, 437 KB

english, 2014

Stimulation by lithium of the interaction between the transcription factor CREB and its co-activator TORC

Журнал:

Bioscience Reports

Рік:

2009

Мова:

english

Файл:

PDF, 574 KB

english, 2009

Impact of mineralocorticoid receptor polymorphisms on urinary electrolyte excretion with and without diuretic drugs

Dalila, Nawar, Brockmöller, Jürgen, Tzvetkov, Mladen Vassilev, Schirmer, Markus, Haubrock, Martin, Vormfelde, Stefan Viktor

Журнал:

Brockmöller, Jürgen, Tzvetkov, Mladen V

Рік:

2015

Мова:

english

Файл:

PDF, 1.61 MB

english, 2015

Polymorphic OCT1 : a valid biomarker, but for which drugs?

Журнал:

Tzvetkov, Mladen Vassilev, Meineke, Ingolf, Sehrt, Daniel, Vormfelde, Stefan Viktor, Brockmöller, Jürgen

Рік:

2013

Мова:

english

Файл:

PDF, 908 KB

english, 2013

Amelogenin-based sex identification as a strategy to control the identity of DNA samples in genetic association studies

Журнал:

Hasheminasab, Sayed-Mohammad, Tzvetkov, Mladen V, Schumann, Christian, Rüdiger, Stefan, Boeck, Stefan, Heinemann, Volker, Kächele, Volker, Steffens, Michael, Scholl, Catharina, Hichert, Vivien, Seuffe

Рік:

2010

Мова:

english

Файл:

PDF, 1.49 MB

english, 2010

High-throughput screening identified inherited genetic variations in the EGFR pathway contributing to skin toxicity of EGFR inhibitors

Журнал:

Seitz, Tina, Stalmann, Robert, Dalila, Nawar, Chen, Jiayin, Pojar, Sherin, Dos Santos Pereira, Joao N., Krätzner, Ralph, Brockmöller, Jürgen, Tzvetkov, Mladen V.

Рік:

2015

Мова:

english

Файл:

PDF, 1.27 MB

english, 2015

Global genetic analyses reveal strong inter-ethnic variability in the loss of activity of the organic cation transporter OCT1

Журнал:

Genome Medicine

Рік:

2015

Мова:

english

Файл:

PDF, 9.07 MB

english, 2015

Common genetic variations in human brain-specific tryptophan hydroxylase-2 and response to antidepressant treatment

Tzvetkov, Mladen Vassilev, Brockmöller, Jürgen, Roots, Ivar, Kirchheiner, Julia

Журнал:

Meineke, Cornelia, Tzvetkov, Mladen Vassilev, Bokelmann, Kristin, Oetjen, Elke, Hirsch-Ernst, Karen, Kaiser, Rolf, Brockmöller, Jürgen

Рік:

2008

Мова:

english

Файл:

PDF, 206 KB

english, 2008

Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene

Журнал:

Heller, Tanja, Kirchheiner, Julia, Armstrong, Victor W, Luthe, Hilmar, Tzvetkov, Mladen, Brockm??ller, J??rgen, Oellerich, Michael

Рік:

2008

Мова:

english

Файл:

PDF, 349 KB

english, 2008

AmpliChip CYP450 GeneChip??: A New Gene Chip That Allows Rapid and Accurate CYP2D6 Genotyping

Журнал:

Therapeutic Drug Monitoring

Рік:

2006

Мова:

english

Файл:

PDF, 79 KB

english, 2006

Bioinformatic and functional analysis of TGFBR1 polymorphisms

Schirmer, Markus A., Hoffmann, Arne O., Campean, Radu, Janke, Jörg H., Zidek, Laura M., Hoffmann, Marion, Kruse, Moritz, Sehrt, Daniel, Tzvetkov, Mladen V., Rave-Fränk, Margret, Brockmöller, Jürgen

Журнал:

Kürten, Cornelius, Tzvetkov, Mladen, Ellenrieder, Volker, Schwörer, Harald

Рік:

2009

Мова:

english

Файл:

PDF, 346 KB

english, 2009

Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families

Chen, Jiayin, Brockmöller, Jürgen, Seitz, Tina, König, Jörg, Chen, Xijing, Tzvetkov, Mladen V.

Журнал:

Biological Chemistry

Рік:

2016

Мова:

english

Файл:

PDF, 552 KB

english, 2016

Schwere Hypoglykämie nach Tramadol-Einnahme bei einer nicht-diabetischen Patientin

Журнал:

DMW - Deutsche Medizinische Wochenschrift

Рік:

2016

Мова:

german

Файл:

PDF, 590 KB

german, 2016

Pharmacogenetic screening for drug therapy: From single gene markers to decision making in the next generation sequencing era

Tzvetkov, Mladen, von Ahsen, Nicolas

Журнал:

Pathology

Рік:

2012

Мова:

english

Файл:

PDF, 199 KB

english, 2012

Erratum to: Tropane alkaloids as substrates and inhibitors of human organic cation transporters of the SLC22 (OCT) and the SLC47 (MATE) families

Chen, Jiayin, Brockmöller, Jürgen, Seitz, Tina, König, Jörg, Tzvetkov, Mladen V., Chen, Xijing

Журнал:

Biological Chemistry

Рік:

2017

Мова:

english

Файл:

PDF, 74 KB

english, 2017

Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters

Johannes Matthaei,Mladen V. Tzvetkov,Valerie Gal…

Журнал:

Genome Medicine

Рік:

2016

Мова:

english

Файл:

PDF, 732 KB

english, 2016

Loss-of-function polymorphisms in the organic cation transporter OCT1 are associated with reduced postoperative tramadol consumption

Stamer, Ulrike M., Musshoff, Frank, Stüber, Frank, Brockmöller, Jürgen, Steffens, Michael, Tzvetkov, Mladen V.

Журнал:

PAIN®

Рік:

2016

Мова:

english

Файл:

PDF, 486 KB

english, 2016

The FER rs4957796 TT genotype is associated with unfavorable 90-day survival in Caucasian patients with severe ARDS due to pneumonia

Hinz, José, Büttner, Benedikt, Kriesel, Fabian, Steinau, Maximilian, Frederik Popov, Aron, Ghadimi, Michael, Beissbarth, Tim, Tzvetkov, Mladen, Bergmann, Ingo, Mansur, Ashham

Журнал:

Scientific Reports

Рік:

2017

Мова:

english

Файл:

PDF, 1.07 MB

english, 2017

OCT1 pharmacogenetics in pain management: is a clinical application within reach?

Tzvetkov, Mladen V

Журнал:

Gorboulev, Valentin, Rehman, Saba, Albert, Christoph Michael, Roth, Ursula, Meyer, Marleen Julia, Tzvetkov, Mladen Vassielev, Mueller, Thomas Dieter, Koepsell, Hermann

Рік:

2017

Мова:

english

Файл:

PDF, 510 KB

english, 2017

Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake.

Журнал:

Molecular Pharmacology

Рік:

2018

Мова:

english

Файл:

PDF, 1.57 MB

english, 2018

OCT1 deficiency affects hepatocellular concentrations and pharmacokinetics of cycloguanil, the active metabolite of the antimalarial drug proguanil

Matthaei, Johannes, Seitz, Tina, Jensen, Ole, Tann, Annabelle, Prukop, Thomas, Tadjerpisheh, Sina, Brockmöller, Jürgen, Tzvetkov, Mladen V

Журнал: